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Just started 3 weeks ago and noticed a weight gain of about 3 pound right away. It works though. Noticed no night sweats or insomnia starting the first night. Worth the trade off so far. Worried about the weight gain though.



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I had a hysterectomy years ago. I find estradiol hard to swallow because of its shape. I was taking Premarin and it was much easier to swallow due to its outer shell.

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